Table 1:
Comparison of baseline parameters and response to thrombolysis based on the number of sections with FLAIR hyperintense vesselsa
| Visible FHV on ≤4 Sections | Visible FHV on >4 Sections | P Value | |
|---|---|---|---|
| No. | 30 | 32 | |
| Age (yr) (mean) (SD) | 71 (10.8) | 71.9 (16.5) | .42 |
| Time to MRI in min (median) (IQR) | 88.5 (72–103) | 93.5 (61–121) | .98 |
| NIHSS score on admission (median) (IQR) | 5 (4–13) | 14.5 (11–18) | <.001 |
| NIHSS score on day 2 (median) (IQR) | 3 (1–5) | 5 (2–17) | .03 |
| TOAST | .05 | ||
| Cardioembolic (%) (No.) | 40.7 (11) | 36.7 (11) | |
| Macroangiopathic (%) (No.) | 37 (10) | 63.3 (19) | |
| Microangiopathic (%) (No.) | 0 (0) | 0 (0) | |
| Other (%) (No.) | 7.4 (2) | 0 (0) | |
| Competing causes (%) (No.) | 14.8 (4) | 0 (0) | |
| Baseline lesion volume (mL) (median) (IQR) | 1.6 (.3–4.9) | 8.1 (2.4–20.6) | <.01 |
| Infarct growth (median) (IQR) | 1.2 (0.2–12.7) | 12.8 (2.5–43.9) | <.01 |
| Perfusion-diffusion mismatch (%) (No.) | 67.7 (21) | 96.9 (31) | <.01 |
| Baseline perfusion deficit (mL) (median) (IQR) | 24.8 (14.5–54.6) | 118 (82–175) | <.001 |
| Tmax ≥2 sec | 30 (16.7–97.1) | 155 (115.7–191.2) | <.001 |
| Tmax ≥8 sec | 10.3 (3.7–27.2) | 87.2 (62.5–123.7) | <.001 |
| HIR | 0.28 (0.07–0.47) | 0.61 (0.44–0.73) | <.01 |
| Vessel occlusion size: | .29 | ||
| Large (%) (No.) | 20 (6) | 9.4 (3) | |
| Medium (%) (No.) | 80 (24) | 90.6 (29) | |
| Small (%) (No.) | 0 (0) | 0 (0) | |
| Recanalization (%) (No.) | 53.3 (16) | 74.2 (23) | .11 |
| Favorable outcome at 3 months (%) (No.) | 66.7 (20) | 38.7 (12) | .02 |
a
A Fisher exact test and Mann-Whitney U test were used for categoric and continuous variables, respectively.