Graph of TII values in meningiomas and metastases compared with TIIs in gliomas. The mean TII of meningiomas and metastases is zero, with a 95% CI between −15 and 15. The mean TII of gliomas is 64, with a 95% CI between 38 and 90. Reprinted with permission from Lu S, Ahn D, Johnson G, et al. Diffusion-tensor MR imaging of intracranial neoplasia and associated peritumoral edema: introduction of the tumor infiltration index. Radiology 2004;232:221–28.24