Fig 4.

A representative low ADC lesion in a patient with glioblastoma demonstrates faint rim-enhancement on T1-weighted MR imaging with and without contrast, low signal intensity on ADC, hyperintensity on DWI, and hypermetabolic activity on ¹⁸F-FDOPA PET scans. The standardized rCBV in the region of interest (normalized to normal-appearing white matter) was 0.44 in this patient. The legend shows standardized rCBV scaled 0–20,000 astronomical units. Another representative lesion demonstrates the above features, as well as hypoperfusion on a DSC perfusion MR imaging. The legend shows relative ¹⁸F-FDOPA uptake with the standardized uptake value (SUV) normalized to basal ganglia, with the mean SUV in this patient of 0.43.