Table 3:
Anatomic Region | Hemisphere | AD (×10−3mm2/s) (Mean) |
RD (×10−3mm2/s) (Mean) |
MD (×10−3mm2/s) (Mean) |
||||||
---|---|---|---|---|---|---|---|---|---|---|
HIV− | HIV+ | P Value | HIV− | HIV+ | P Value | HIV− | HIV+ | P Value | ||
Genu of corpus callosum | Bilateral | 1.62 ± 0.08 | 1.58 ± 0.08 | .16 | 0.36 ± 0.03 | 0.40 ± 0.06 | .004 | 0.78 ± 0.03 | 0.79 ± 0.05 | .22 |
Body of corpus callosum | Bilateral | 1.78 ± 0.06 | 1.78 ± 0.06 | .99 | 0.41 ± 0.05 | 0.49 ± 0.07 | .0003a | 0.87 ± 0.04 | 0.92 ± 0.05 | .002a |
Splenium | Bilateral | 1.66 ± 0.06 | 1.67 ± 0.05 | .41 | 0.33 ± 0.03 | 0.37 ± 0.04 | .0003a | 0.77 ± 0.02 | 0.80 ± 0.03 | .001a |
Superior corona radiata | Left | 1.21 ± 0.04 | 1.20 ± 0.03 | .33 | 0.53 ± 0.02 | 0.56 ± 0.04 | .0003a | 0.76 ± 0.02 | 0.78 ± 0.03 | .01 |
Superior corona radiata | Right | 1.26 ± 0.05 | 1.26 ± 0.04 | .78 | 0.49 ± 0.02 | 0.53 ± 0.03 | .00009a | 0.74 ± 0.02 | 0.77 ± 0.02 | .001a |
Posterior corona radiata | Left | 1.23 ± 0.06 | 1.23 ± 0.03 | .81 | 0.59 ± 0.03 | 0.62 ± 0.03 | .002a | 0.80 ± 0.03 | 0.82 ± 0.02 | .02 |
Posterior corona radiata | Right | 1.26 ± 0.04 | 1.25 ± 0.03 | .32 | 0.57 ± 0.03 | 0.61 ± 0.04 | .002a | 0.80 ± 0.03 | 0.82 ± 0.04 | .05 |
Frontal WM | Left | 1.35 ± 0.07 | 1.32 ± 0.05 | .22 | 0.44 ± 0.03 | 0.48 ± 0.04 | .001a | 0.74 ± 0.03 | 0.76 ± 0.03 | .09 |
Frontal WM | Right | 1.37 ± 0.06 | 1.32 ± 0.07 | .02 | 0.40 ± 0.03 | 0.48 ± 0.03 | .0003a | 0.72 ± 0.03 | 0.73 ± 0.03 | .21 |
Pre-/postcentral gyrus WM | Left | 1.32 ± 0.06 | 1.29 ± 0.06 | .14 | 0.47 ± 0.03 | 0.50 ± 0.03 | .0007a | 0.75 ± 0.02 | 0.76 ± 0.02 | .06 |
Pre-/postcentral gyrus WM | Right | 1.30 ± 0.04 | 1.27 ± 0.04 | .01 | 0.44 ± 0.02 | 0.48 ± 0.03 | .00009a | 0.73 ± 0.02 | 0.74 ± 0.02 | .08 |
Parietal WM | Left | 1.31 ± 0.05 | 1.31 ± 0.05 | .94 | 0.57 ± 0.04 | 0.61 ± 0.03 | .001a | 0.82 ± 0.03 | 0.84 ± 0.03 | .02 |
Parietal WM | Right | 1.29 ± 0.06 | 1.27 ± 0.04 | .28 | 0.58 ± 0.03 | 0.62 ± 0.05 | .002a | 0.81 ± 0.03 | 0.84 ± 0.04 | .07 |
SLF | Left | 1.11 ± 0.04 | 1.09 ± 0.03 | .13 | 0.54 ± 0.03 | 0.57 ± 0.04 | .004 | 0.73 ± 0.02 | 0.75 ± 0.03 | .05 |
Note:—HIV- indicates HIV-negative controls; HIV+, HIV-positive subjects.
P < .05/14 ≈ .0035 (Bonferroni-corrected for multiple comparisons).