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. 2015 Nov;36(11):2163–2169. doi: 10.3174/ajnr.A4417

Table 3:

Group differences in diffusivity indices from VOIs

Anatomic Region Hemisphere AD (×10−3mm2/s) (Mean)
RD (×10−3mm2/s) (Mean)
MD (×10−3mm2/s) (Mean)
HIV− HIV+ P Value HIV− HIV+ P Value HIV− HIV+ P Value
Genu of corpus callosum Bilateral 1.62 ± 0.08 1.58 ± 0.08 .16 0.36 ± 0.03 0.40 ± 0.06 .004 0.78 ± 0.03 0.79 ± 0.05 .22
Body of corpus callosum Bilateral 1.78 ± 0.06 1.78 ± 0.06 .99 0.41 ± 0.05 0.49 ± 0.07 .0003a 0.87 ± 0.04 0.92 ± 0.05 .002a
Splenium Bilateral 1.66 ± 0.06 1.67 ± 0.05 .41 0.33 ± 0.03 0.37 ± 0.04 .0003a 0.77 ± 0.02 0.80 ± 0.03 .001a
Superior corona radiata Left 1.21 ± 0.04 1.20 ± 0.03 .33 0.53 ± 0.02 0.56 ± 0.04 .0003a 0.76 ± 0.02 0.78 ± 0.03 .01
Superior corona radiata Right 1.26 ± 0.05 1.26 ± 0.04 .78 0.49 ± 0.02 0.53 ± 0.03 .00009a 0.74 ± 0.02 0.77 ± 0.02 .001a
Posterior corona radiata Left 1.23 ± 0.06 1.23 ± 0.03 .81 0.59 ± 0.03 0.62 ± 0.03 .002a 0.80 ± 0.03 0.82 ± 0.02 .02
Posterior corona radiata Right 1.26 ± 0.04 1.25 ± 0.03 .32 0.57 ± 0.03 0.61 ± 0.04 .002a 0.80 ± 0.03 0.82 ± 0.04 .05
Frontal WM Left 1.35 ± 0.07 1.32 ± 0.05 .22 0.44 ± 0.03 0.48 ± 0.04 .001a 0.74 ± 0.03 0.76 ± 0.03 .09
Frontal WM Right 1.37 ± 0.06 1.32 ± 0.07 .02 0.40 ± 0.03 0.48 ± 0.03 .0003a 0.72 ± 0.03 0.73 ± 0.03 .21
Pre-/postcentral gyrus WM Left 1.32 ± 0.06 1.29 ± 0.06 .14 0.47 ± 0.03 0.50 ± 0.03 .0007a 0.75 ± 0.02 0.76 ± 0.02 .06
Pre-/postcentral gyrus WM Right 1.30 ± 0.04 1.27 ± 0.04 .01 0.44 ± 0.02 0.48 ± 0.03 .00009a 0.73 ± 0.02 0.74 ± 0.02 .08
Parietal WM Left 1.31 ± 0.05 1.31 ± 0.05 .94 0.57 ± 0.04 0.61 ± 0.03 .001a 0.82 ± 0.03 0.84 ± 0.03 .02
Parietal WM Right 1.29 ± 0.06 1.27 ± 0.04 .28 0.58 ± 0.03 0.62 ± 0.05 .002a 0.81 ± 0.03 0.84 ± 0.04 .07
SLF Left 1.11 ± 0.04 1.09 ± 0.03 .13 0.54 ± 0.03 0.57 ± 0.04 .004 0.73 ± 0.02 0.75 ± 0.03 .05

Note:—HIV- indicates HIV-negative controls; HIV+, HIV-positive subjects.

a

P < .05/14 ≈ .0035 (Bonferroni-corrected for multiple comparisons).