Table 1:
Demographic and neuropathologic data of subjects
| Case No. | Noa | Sex | Age (yr) | PMD (h:min)b | DD (yr) | MS Type | COD |
|---|---|---|---|---|---|---|---|
| MS | |||||||
| 1 | M | 80 | 6:05 | 45 | SPMS | Pneumonia | |
| 2 | F | 81 | 3:30 | 27 | PPMS | Pneumonia | |
| 3 | M | 75 | 10:10 | 50 | NA | Pneumonia | |
| 4 | F | 66 | 7:30 | 17 | NA | Pulmonary hypertension | |
| 5 | M | 71 | 4:00 | 15 | SPMS | Pulmonary carcinoma | |
| 6 | F | 54 | 6:00 | 16 | SPMS | Liver cancer | |
| 7 | M | 63 | 4:30 | 25 | SPMS | Pneumonia | |
| 8 | M | 78 | 3:00 | 33 | SPMS | Euthanasia | |
| 9 | M | 59 | 5:00 | 21 | SPMS | Euthanasia | |
| 10 | M | 56 | 10:10 | 13 | NA | Suicide | |
| 11 | F | 56 | 8:25 | 32 | SPMS | Pneumonia | |
| 12 | F | 54 | 3:30 | 31 | SPMS | Heart failure | |
| 13 | M | 58 | 4:00 | 27 | SPMS | Pneumonia | |
| 14 | F | 95 | 6:30 | 55 | SPMS | Unknown | |
| 15 | F | 81 | 6:30 | 21 | SPMS | Heart failure | |
| Mean | 68.5 ± 12.7 | 5:56 ± 2:27 | 28.5 ± 12.9 | ||||
| Control | |||||||
| 20 | 4 | F | 72 | >24:00 | – | – | Myocardial infarct |
| 21 | 3 | F | 58 | <24:00 | – | – | Breast cancer |
| 22 | 3 | F | 76 | <24:00 | – | – | Pneumonia |
| 23 | 2 | F | 76 | <8:00 | – | – | Pneumonia |
| Mean | 70.5 ± 8.5 |
Note:—PMD indicates postmortem delay; DD, disease duration since diagnosis; SPMS, secondary-progressive MS; PPMS, primary-progressive MS; COD, cause of death; NA, unavailable/unknown; –, not applicable.
a
The numbers indicate number of hemispheric sections included per case.
b
Control cases are not part of the rapid postmortem examination program and therefore have a longer PMD.