Fig 2.

Typical infratentorial cPML in another HIV-positive patient classically involving the middle cerebellar peduncle (left). A and B, This lesion also has diffusion restriction at the anterolateral advancing edge (high DWI signal intensity and low ADC value, arrows) and diffusion facilitation at the center as evidenced by the DWI (A) and the ADC map (B). C and D, The lesion shows typical hypointensity on the T1-weighted sequence (C) and hyperintensity on FLAIR (D). Note, there are no mass effect. There is no enhancement in the postcontrast T1-weighted sequence (E).