Fig 4.

Highlighted tracts display significant correlations between TBSS differences and performance on neuropsychological tests (P < .05). Red-highlighted tracts represent positive correlations, and blue-highlighted tracts represent negative correlations. For patients with MS, decreased neuropsychological scores significantly correlated with decreased FA and increased MD for each of the neuropsychological tests. For patients with NPSLE, decreased Delis-Kaplan Executive Function System scores significantly correlated with decreased FA. For HCs, increased PASAT scores correlated significantly with decreased MD. CVLT2 indicates California Verbal Learning Test, 2nd ed; BVMT-R, Brief Visuospatial Memory Test-Revised; D-KEFS, Delis-Kaplan Executive Function System; SDMT, Symbol Digit Modalities Test; dNPSLE, neuropsychiatric systemic lupus erythematosus with diffuse syndromes.