Table 4.
Results of 2 Different Binary Logistic Regression Analyses With Schizophrenia (vs healthy controls) and Nonresponders to Treatment (NRTT) vs Partial Responders to Treatment (PRTT) as Dependent Variables and the Biomarkers as Explanatory Variables
| Dichotomies | Explanatory Variables | B | SE | Wald | df | P | OR | 95% CI |
|---|---|---|---|---|---|---|---|---|
| Schizophrenia/controls | DKK1 | 0.459 | 0.240 | 5.60 | 1 | .018 | 1.77 | 1.10–2.83 |
| HMGB1 | 1.602 | 0.282 | 32.26 | 1 | <.001 | 4.96 | 2.86–8.63 | |
| NRTT/PRTT | IL-6 | 1.039 | 0.221 | 16.44 | 1 | <.001 | 2.83 | 1.71–4.67 |
| CCL11 | 0.512 | 0.211 | 5.37 | 1 | .020 | 1.67 | 1.08–2.57 |
Note: OR, odds ratio; 95% CI, 95% confidence intervals; CCL11, CC-motif chemokine 11 or eotaxin; DKK1, Dickkopf protein 1; HMGB1, high mobility group box 1 protein; IL, interleukin.