Table 6.
Results of Multiple Regression Analysis With Neurocognitive Test Scores as Dependent Variables
| Dependent Variables | Explanatory Variables | β | t | P | F model | df | P | R 2 |
|---|---|---|---|---|---|---|---|---|
| #1. List learning | Model | 9.95 | 4/153 | <.001 | .206 | |||
| HMGB1 | −.228 | −3.08 | .002 | |||||
| Education | .244 | 3.35 | .001 | |||||
| DKK1 | −.179 | −2.45 | .015 | |||||
| CCL11 | −.152 | −2.08 | .039 | |||||
| #2. Digit sequencing task | Model | 19.30 | 4/153 | <.001 | .335 | |||
| HMGB1 | −.402 | −5.84 | <.001 | |||||
| IL-6 | −.192 | −2.78 | .006 | |||||
| Education | .163 | 2.42 | .017 | |||||
| CCL11 | −.160 | −2.40 | .018 | |||||
| #3. Category instances | Model | 13.37 | 3/154 | <.001 | .207 | |||
| HMGB1 | −.292 | −4.01 | <.001 | |||||
| DKK1 | −.242 | −3.33 | .001 | |||||
| Education | .165 | 2.28 | .024 | |||||
| #4. COWA | Model | 38.83 | 2/155 | <.001 | .334 | |||
| HMGB1 | −.490 | −7.23 | <.001 | |||||
| IL-6 | −.208 | −3.07 | .003 | |||||
| #5. Symbol coding | Model | 50.34 | 2/154 | <.001 | .395 | |||
| HMGB1 | −.583 | −9.20 | <.001 | |||||
| DKK1 | .165 | −2.61 | .010 | |||||
| #6. Tower of London | Model | 26.36 | 3/154 | <.001 | .339 | |||
| HMGB1 | −.436 | −6.56 | <.001 | |||||
| Education | .279 | 4.32 | <.001 | |||||
| DKK1 | −.153 | −2.30 | .023 |
Note: CCL11, CC-motif chemokine 11 or eotaxin; DKK1, Dickkopf protein 1; FTD, formal thought disorders; HMGB1, high mobility group box 1 protein; IL, interleukin; PMR, psychomotor retardation; SANS, Scale for the Assessment of Negative Symptoms.