Table 5:

DTI measures of white matter pathways in pediatric CIS-baseline MRI

	MCIS			PCISWOE			PCISWE
	Patients	Controls	P Value	Patients	Controls	P Value	Patients	Controls	P Value
CC
Mean ADC (± SD)	0.87 (0.086)	0.84 (0.073)	.46	0.95 (0.11)	0.89 (0.056)	.10	1.01 (0.12)	1.02 (0.093)	.67
Mean FA (± SD)	0.53 (0.042)	0.56 (0.033)	.20	0.55 (0.030)	0.58 (0.049)	.15	0.56 (0.059)	0.55 (0.039)	.87
CP
Mean ADC (± SD)	0.72 (0.062)	0.72 (0.056)	.75	0.74 (0.060)	0.73 (0.048)	.19	0.80 (0.044)	0.79 (0.030)	.61
Mean FA (± SD)	0.55 (0.032)	0.59 (0.040)	.045a	0.59 (0.052)	0.60 (0.063)	.67	0.60 (0.073)	0.60 (0.059)	.97
PLIC
Mean ADC (± SD)	0.72 (0.058)	0.71 (0.051)	.68	0.73 (0.063)	0.72 (0.053)	.33	0.76 (0.030)	0.76 (0.036)	.77
Mean FA (± SD)	0.53 (0.013)	0.56 (0.041)	.067	0.57 (0.053)	0.58 (0.052)	.66	0.59 (0.087)	0.60 (0.039)	.65
LAF
Mean ADC (± SD)	0.78 (0.051)	0.73 (0.051)	.018a	0.79 (0.057)	0.77 (0.051)	.33	0.84 (0.038)	0.84 (0.035)	.73
Mean FA (± SD)	0.45 (0.021)	0.46 (0.037)	.41	0.46 (0.018)	0.49 (0.039)	.041a	0.47 (0.083)	0.46 (0.051)	.65

Note:—CP indicates cerebral peduncle; CC, corpus callosum.

^aStatistically significant.