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. 2013 Dec;34(12):2259–2264. doi: 10.3174/ajnr.A3631

Table 1:

Comparison of different types of atherosclerotic plaques between VH-IVUS and histologic sections (as reference standard)

Category of Plaque Plaque Classification by Histological Analysis Plaque Classification by VH-IVUS Analysis
True-Positive True-Negative False-Positive False-Negative Sensitivity Specificity PPV NPV
No plaque 2 2 32 0 0 100 100 100 100
Pathologic intima thickening 6 3 28 0 3 50 100 100 90.3
Fibroatheroma 19 15 11 4 4 78.9 73.3 78.9 73.3
Calcified fibroatheromaa 0 0 33 1 0 0 97 0 100
Thin-cap fibroatheroma 3 2 30 1 1 66.6 96.7 66.6 96.7
Calcified thin-cap fibroatheroma 2 1 31 1 1 50 96.8 50 96.8
Fibrocalcific atheroma 2 2 32 0 0 100 100 100 100
Total 34 25 197 7 9 73.5 96.6 78.1 95.6

PPV indicates positive predictive value; NPV, negative predictive value.

a

Number is small and requires cautious interpretation of false-positive or false-negative values.