Table 3.
F values for significant main effects of sex on neurotransmitter concentrations for LgA and naïve groups (P < 0.05). Arrows indicate the direction of effects of sex compared to males. Degrees of freedom are 1, 28 for all comparisons except for 5-HIAA for 4MMC and NE for α-PVP in hippocampus, which have 1, 27 degrees of freedom, and NE in PFC for 4MMC and α-PVP, which have 1, 19, and 1, 15 degrees of freedom, respectively.
| Brain Region | 5-HT | 5-HIAA | NE | GLU |
|---|---|---|---|---|
| α-PVP | ||||
| Amygdala | ↑ 15.96 | ↑ 4.46 | ||
| Hippocampus | ↑ 24.71 | |||
| Hypothalamus | ↑ 11.94 | ↓ 5.27 | ||
| PFC | ↑ 5.03 | |||
| Striatum | ↑ 9.22 | ↑ 5.85 | ||
| 4MMC | ||||
| Amygdala | ↑ 10.34 | |||
| Hippocampus | ↓ 17.67 | ↓ 5.99 | ||
| Hypothalamus | ↓ 5.69 | ↓ 4.28 | ||
| PFC | ↑ 8.68 | |||
| Striatum | ↑ 9.22 | |||