Table 1:
Patient Characteristics
| Variables | Control (n=11) | ICM (n=20) | p-value |
|---|---|---|---|
| Race/Ethnicity | |||
| White/Not Hispanic or Latino, n (%) | 9 (82) | 16 (80) | 0.99 |
| Other, n (%) | 2 (18) | 4 (20) | |
| Male sex, n (%) | 6 (55) | 12 (60) | 0.77 |
| Age at Tissue Acquisition, years | 44±4 | 52±3 | 0.15 |
| Height, cm | 169±3 | 170±2 | 0.86 |
| Weight, kg | 78±5 | 81±4 | 0.59 |
| BMI, kg/m2 | 27.2±2.0 | 28.0±1.2 | 0.71 |
| BSA, m2 | 1.9±0.1 | 1.9±0.0 | 0.59 |
| Pre-Tissue Acquisition Echocardiographic Measurements | |||
| LVEF, % | 65±3 | 22±3 | <0.0001 |
| LVEDD, cm | 4.1±0.2 | 6.5±0.3 | <0.0001 |
| LVEDD index, cm/m2 | 2.2±0.1 | 3.4±0.2 | <0.0001 |
| LVESD, cm | 2.8±0.2 | 5.8±0.4 | <0.0001 |
| LVESD index, cm/m2 | 1.5±0.1 | 3.1±0.2 | <0.0001 |
| Pre-Tissue Acquisition Hemodynamic Measurements | |||
| Systolic Blood Pressure, mmHg | 119±6 | 109±4 | 0.14 |
| Diastolic Blood Pressure, mmHg | 68±3 | 70±2 | 0.73 |
| Mean Right Atrial Pressure, mmHg | 11±2 | 9±1 | 0.36 |
| Cardiac Index, L/min/m2 | 3.9±0.4 | 2.0±0.1 | <0.001 |
| Pre-Tissue Acquisition Laboratory Values | |||
| Sodium, mmol/L | 150±3 | 138±1 | 0.006 |
| Creatinine, mg/dL | 1.3±0.2 | 1.1±0.1 | 0.45 |
| Hemoglobin, g/dL | 9.4±0.5 | 12.8±0.5 | <0.001 |
Characteristics of healthy heart donors and end-stage ischemic cardiomyopathy heart donors included in the study. Data are shown as mean ± standard error. Control vs ICM were compared using t-test for quantitative data and Fisher’s exact test for categorical data.