Table 3:

Number of times a constraint was violated in an adaptive plan.

	Case 1	Case 2	Case 3	Case 4	Case 5	Case 6	Case 7	Case 8	Case 9	Case 10
Treatment site	Larynx (true vocal cord)	Larynx (true vocal cord)	Oropharynx (base of tongue)	Orbit	Hypopharynx (pyriform sinus)	Oropharynx (tonsil)	Nasosinus	Larynx (true vocal cord)	Oral cavity (oral tongue)	Oropharynx (tonsil)
Total number of MR-linac fractions	24	24	26	4	25	29	28	27	33	33
CTV (high dose)	0	2	2	0	0	2	1	2	3	2
PTV (high dose)	1							6
Parotid (ipsi)	•	•	26*†	0	0	29*†	0	•	31*†	7
Parotid (contra)	•	•	26*†	0	0	0	0	•	2	0
Cochlea (ipsi)	•	•	0	0	0	15	0	•	14†	2
Cochlea (contra)	•	•	0	0	0	0	4	•	0	0
Brainstem	•	•	0	0	0	0	0	•	0	0
Spinal cord	0	0	1	0	0	0	0	0	0	0
Carotid (contra)	0	0	•	•	•	•	•	0	•	•
Brachial plexus (ipsi)	•	•	1	•	•	•	•	•	2	0
Brachial plexus (contra)	•	•	7	•	•	•	•	•	0	0

^•constraint was not used for optimization

^*constraint was not met in initial reference plan

^†constraint was not met in summation plan