Table 2:
Spectroscopy results
| Metabolite | Controls (n = 15) | ALS-All (n = 24) | El Escorial Criteria |
ALS-FTD (n = 2) | ||
|---|---|---|---|---|---|---|
| Possible (n = 5) | Probable (n = 15) | Definite (n = 4) | ||||
| NAA/mIns | 1.95 ± 0.27 | 1.62 ± 0.31 | 1.65 ± 0.23 | 1.63 ± 0.37 | 1.53 ± 0.10 | 1.10 ± 0.19 |
| NAA (mmol/L) | 9.82 ± 1.76 | 8.92 ± 1.29 | 9.22 ± 0.65 | 8.77 ± 1.36 | 9.14 ± 1.80 | 7.02 ± 2.02 |
| mIns (mmol/L) | 5.06 ± 0.76 | 5.63 ± 0.96 | 5.67 ± 0.89 | 5.06 ± 0.75 | 5.99 ± 1.14 | 6.34 ± 0.71 |
Note:—Spectroscopy quantities are mean ± SD. Patients are categorized according to disease stage by El Escorial Criteria or presence of dementia (ALS-FTD).