Table 2:

Change of neurologic scores during a median of 12 months

Score	No.	Baseline	Follow-Upa	P Valueb	Split Thresholdc	Progression	Nonprogression
EDSS (median) (range)	44	2.0 (0–5.5)	2.0 (0–5.5)	0.950	≥0.5c	9	35
MSFC (mean) (SD)	38	0.550 (0.415)	0.549 (0.475)	0.969	<−0.047	13	25
TWT (mean) (SD)d	39	−0.431 (0.082)	−0.412 (0.098)	0.105	>0.013	16	23
9-HPT (mean) (SD)e	40	0.780 (0.735)	0.736 (0.837)	0.382	<−0.113	15	25
PASAT (mean)f	39	0.460 (0.693)	0.531 (0.800)	0.414	<−0.101	8	31

^aAnnualized values for MSFC, raw values for EDSS (for details see “Materials and Methods”).

^bTwo-sided Wilcoxon signed rank test (EDSS) and paired Studentt test (MSFC, annualized follow-up values), respectively.

^cSee “Materials and Methods” section for details on threshold definition.

^dTWT.

^e9-HPT.

^fPASAT.