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. 2013 Sep;34(9):1764–1768. doi: 10.3174/ajnr.A3515

Table 1:

Summary of published randomized clinical trials of surgery versus coiling for ruptured aneurysms

Kuopio ISAT BRAT
Period February 1995 to August 1997 1997 to September 2002 March 2003 to January 2007
Single-center/multicenter Single Multicenter Single
Enrollment <72 hours <28 days <14 days
Total patients screened 242 9559 725
Patients enrolled 109 2143 471
Mean age (years)
    Endovascular 49 52 54
    Surgery 50 52 53
No. of patients allocated endovascular 52 1073 233
No. of patients allocated surgery 57 1070 238
Good grade, n (% of total) 93 (85.3) 2018 (94.2) 380 (80.7)
Poor grade, n (% of total) 16 (13.7) 94 (5.8) 91 (19.3)
Crossovers
    From endovascular to surgery 12 9 75
    From surgery to endovascular 4 38 4