Table 2.
Clinical Parameters and Outcomes According to Presence or Absence of Right Ventricular Dysfunction
| Variable | RV Dysfunction (n = 181) | No RV Dysfunction (n = 194) | P |
|---|---|---|---|
| Clinical parameters | |||
| Age, y | 64.7 (16.0) | 60.9 (16.5) | .03 |
| APACHE II | 27.12 (10.13) | 24.43 (10.19) | .02 |
| Elixhauser Comorbidity Index | 10.0 (3.7) | 8.9 (3.9) | .004 |
| Fluid receipt 6 hours before echo, mL | 1,962 (2,028) | 2191 (2,184) | .24 |
| Receipt of vasopressors during echo; No. (%) | 63 (34.8) | 82 (42.3) | .17 |
| Norepinephrine equivalent dose at echo (among those receiving pressors), μg/kg/min | 0.21 (0.25) | 0.22 (0.26) | .12 |
| Ventilated during echo; No. (%) | 52 (28.7) | 47 (24.2%) | .35 |
| Pao2/Fio2 Ratio | 217 (125) | 255 (147) | .02 |
| Clinical outcomes | |||
| 28-Day mortality; No. (%) | 57 (31%) | 31 (16%) | .001 |
| Ventilator-free days | 26 (−1 to 28) | 28 (21-28) | .001 |
| 3-day Δ SOFA | −3 (−7 to −1) | −5 (−7 to −2) | .05 |
| Cardiac OFFD to day 14 | 11 (6-13) | 12 (9-13) | .008 |
| Coagulation OFFD to day 14 | 14 (10-14) | 14 (13-14) | .05 |
| Hepatic OFFD to day 14 | 14 (11-14) | 14 (13-14) | .13 |
| Renal OFFD to day 14 | 13 (6-14) | 14 (12-14) | .001 |
The test for significance is unadjusted for 28-day mortality (primary outcome), and all other P values of secondary outcomes are adjusted using the false discover rate method. Tests for significance for clinical parameters are unadjusted for multiple comparison. OFFD = organ failure-free days; RV = right ventricle; SOFA = sequential organ failure assessment.