Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(a) The stability of conjugate 2 in aqueous acidic solution (pH 5), cell culture media (+ and − HEPES), and human serum at 37 °C. Each experiment was repeated at least once. Error bars show standard deviation. (b) Analysis of different moieties present in solution during incubation of conjugate 2 with human serum using MALDI-TOF mass spectrometry. Inset shows the structure of the peptide-linker fragment released upon acid hydrolysis of conjugate 2.
