Tumor pathologic features by WHO grade, age, location, and rTBF
| Tumor Pathologic Feature | WHO Grade | Mean Agea | Tumor Location | rTBFb |
|---|---|---|---|---|
| High-grade tumors (III and IV) (n=21) | ||||
| Glioblastoma (4) | IV | 13 ± 8.5 | Cerebrum | 3.70 ± 1.89 |
| Anaplastic astrocytoma (1) | III | 11 | Cerebrum | 3.60 |
| CNS PNET (1) | IV | 9 | Thalamus | 1.32 |
| Medulloblastoma (9) | IV | 6.1 ± 3.7 | PF | 2.87 ± 1.74 |
| Primary malignant melanoma (1) | IV | 12 | Cerebrum | 1.70 |
| Anaplastic ependymoma (2) | III | 3 ± 2.8 | PF | 1.99 ± 0.39 |
| CNS ATRT (1) | IV | 4 | Cerebrum | 1.67 |
| Choroid plexus carcinoma (1) | III | 3 months | Lateral ventricle | 7.96 |
| DIPG (1) | III | 7 | Pons | 1.70 |
| Low-grade tumors (I and II) (n=32) | ||||
| Pilocytic astrocytoma (8) | I | 9.4 ± 6.1 | Cerebrum (1), cerebellum (3), brain stem (4) | 1.05 ± 0.19 |
| Hypothalamic astrocytoma (1) | II | 10 | Hypothalamus–third ventricle | 0.99 |
| Angiocentric glioma (1) | I | 15 | Cerebrum | 0.94 |
| DNT (2) | I | 5.5 ± 4.9 | Cerebrum | 0.89 ± 0.13 |
| OPG (4) | I | 4.8 ± 1.5 | Optic chiasm | 0.80 ± 0.09 |
| Choroid plexus papilloma (3) | I | 5.6 ± 3.5 | PF (2), lateral ventricle (1) | 1.13 ± 0.15 |
| Atypical choroid plexus papilloma (1) | II | 2 | PF | 1.34 |
| Ganglioglioma (6) | I | 6.2 ± 6.6 | Cerebrum (5), brain stem (1) | 1.45 ± 0.54 |
| Craniopharyngioma (4) | I | 12.8 ± 4.3 | Suprasellar cistern | 0.99 ± 0.13 |
| Atypical meningioma (1) | II | 8 months | Cerebrum | 1.60 |
| Ependymoma (1) | II | 3 | PF | 1.82 |
| Unspecified grade (n=1) | ||||
| DIPG (1) | II–IV | 6 | Pons | 1.35 |
Note:—ATRT indicates atypical teratoid rhabdoid tumor; PF, posterior fossa; PNET, primitive neuroectodermal tumor.
a
Age in years, unless otherwise specified.
b
rTBF equals the averaged maximal rTBF values from 2 different ROIs within the solid tumor.