Table 2:
Basic characteristics of the study population (N= 3,031)
| N (%) or Mean (SD) | |
|---|---|
| Cohort Source Population | |
| ASD familial enriched risk | 257 (8.5%) |
| ASD non-familial enriched risk | 677 (22.3%) |
| General population | 2,097 (69.2%) |
| Maternal race/ethnicity | |
| Hispanic | 256 (8.5%) |
| Non-Hispanic White | 2,212 (73.0%) |
| Non-Hispanic Black | 280 (9.2%) |
| Non-Hispanic Other | 180 (6.3%) |
| Missing | 103 (3.4%) |
| Maternal education | |
| ≤ High school degree | 520 (17.2%) |
| Some college | 585 (19.3%) |
| ≥ Bachelor’s degree | 1,856 (61.2%) |
| Missing | 70 (2.3%) |
| Parity | |
| No prior child | 1,324 (43.7%) |
| ≥ 1 prior child | 1,580 (52.1%) |
| Missing | 127 (4.2%) |
| Neurodevelopmental Outcomes | |
| ASD diagnosis | 190 (6.3%) |
| No ASD | 2,233 (73.7%) |
| Missing ASD diagnostic information2 | 608 (20.1%) |
| Other non-ASD neurodevelopmental or psychiatric condition1 | 621 (27.8%) |
| Maternal age3 | 31.3 (5.8) |
| Paternal age3 | 33.6 (6.1) |
| Child age at SRS in years | 7.4 (4.9) |
| Gestational age3 | 35.8 (5.8) |
Abbreviations: ASD, Autism Spectrum Disorder; SRS, Social Responsiveness Scale
1
Other condition including: Intellectual disability, non-verbal disability, ADD or ADHD, learning disability, anxiety, depression, language disability. Includes 94 individuals with ASD diagnosis. Percent totals do not sum to 100 due to overlap between groups.
2
These individuals were not included in ROC analyses.
3
Number of individuals with missing values: maternal age (n=31); paternal age (n=909); gestational age (n=46)