Table 2:

Neuroanatomic regions with reduced FA in patients with pSS compared with control subjects

Anatomic Region	MNI Coordinates, mm			Cluster Size
	x	y	z
Right superior corona radiata, superior longitudinal fasciculus, anterior and posterior limb of internal capsule, inferior fronto-occipital fasciculus, uncinate fasciculus	27	8	26	4286
Left anterior thalamic radiation	−8	−18	0	284
Left inferior longitudinal fasciculus, uncinate fasciculus, inferior fronto-occipital fasciculus	−46	7	−20	202
Right anterior thalamic radiation, inferior longitudinal fasciculus	10	−17	5	103
Left anterior limb of internal capsule, anterior thalamic radiation	−23	7	14	92
Left superior corona radiata, superior longitudinal fasciculus, corticospinal tract	−28	−15	21	73
Left anterior thalamic radiation	−16	15	−6	67
Left inferior longitudinal fasciculus, uncinate fasciculus	−44	4	−36	65
Left anterior limb of internal capsule, anterior thalamic radiation	−20	0	11	46
Left inferior longitudinal fasciculus	−16	3	−5	38

Note:—P < .01, family-wise error–corrected. MNI indicates Montreal Neurological Institute.