Table 1:
Summary of clinical characteristics as univariate predictors of overall survival in 46 patients with gliomas
| Characteristics | No. | % | HR (95% CI) | P Value |
|---|---|---|---|---|
| Age | ||||
| 50 Years or younger | 18 | 39.1 | 1 | |
| Older than 50 years | 28 | 60.9 | 7.62 (2.17–26.71) | .002 |
| Karnofsky performance score | ||||
| ≥80 | 25 | 54.3 | 1 | |
| <80 | 21 | 45.7 | 2.86 (1.35–6.08) | .007 |
| Maximal tumor diameter | ||||
| <4 cm | 17 | 37 | 1 | |
| ≥4 cm | 29 | 63 | 1.30 (0.61–2.80) | .50 |
| Surgery | ||||
| Biopsy only | 9 | 19.6 | 1 | |
| Resection | 37 | 80.4 | 4.19 (1.77–9.93) | .001 |
| Histopathologic grade | ||||
| Grade 2 (8 pure astrocytomas, 1 oligodendroglioma) | 9 | 19.6 | 1 | |
| Grade 3 (6 pure astrocytomas, 2 oligoastrocytomas, 1 oligodendroglioma) | 9 | 19.6 | 0.087 (0.83–9.45) | .87 |
| Grade 4 (26 pure astrocytomas, 2 oligoastrocytomas) | 28 | 40.8 | 4.14 (1.25–13.8) | .02 |
| Steroid administration | ||||
| No | 18 | 39.1 | 1 | |
| Yes | 28 | 61.9 | 2.11 (0.96–4.65) | .06 |