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. 2021 Mar 3;9:622835. doi: 10.3389/fbioe.2021.622835

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Copyright © 2021 van Gijtenbeek, Eckhardt, Herrera-Domínguez, Brockmann, Jensen, Geppel, Nielsen, Vindeloev, Neves and Oregaard.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Impact of nsr genotype on bactericidal activity and nisin production. Top row: Well diffusion assays showing the antibacterial activity of CFS collected from indicated strains grown in GM17 for 16 h against the nisin-sensitive L. lactis strain Wg2. Bottom row: Graphs displaying nisin A and nisin¹⁻²⁸ concentrations in CFS collected from indicated strains grown in GM17 for 24 h as measured using HPLC-MS/MS.