Fig 1.

Dedicated MR imaging magnet for small animals and scanning devices. A, 7.4T Bruker Pharmascan (Bruker BioSpin, Rheinstetten, Germany) with a 160-mm horizontal bore (small arrows). A dedicated fixation device for mice brain studies is seen in place, equipped with continuous isofluorane anesthesia (long arrow), respiratory monitoring, and a thermostatic water mat set for 37°C (curved arrows). B, Dedicated mouse head coil (22-mm diameter). C, In-house built poly-methyl-methacrylate bed and fixation device with a Swiss mouse in place.