Patient demographic and clinical information^a

No.	Age (yr)/Sex	Primary Tumor (grade) No.	RT and Timing (mo completed prior to imaging)	Chemotherapy
1	31/M	AA	60 Gy 3D-C (9)	T-RT
		(III)	25 Gy IMRT (2)
2	58/M	GBM	54 Gy 3D-C (22)	T-RT
		(IV)	12 Gy GK (5)
3	36/M	GBM	60 Gy IMRT (3)	T-RT
		(IV)
4	56/M	GBM	60 Gy IMRT (23)	T-RT
		(IV)	30 Gy IMRT (10)
5	45/F	GBM	60 Gy 3D-C (26)	T-RT
		(IV)
6	44/M	GBM	59.4 Gy IMRT (12)	T-RT
		(IV)
7	50/M	GBM	37.5 Gy whole-brain RT (8)	T-RT
		(IV)	30 Gy IMRT (5)
8	42/M	GBM (DD-IV)	60 Gy IMRT (60)	T-RT
9	59/M	GBM	59.4 Gy IMRT (13)	T-RT
		(IV)
10	60/F	Ana. ODG	10 Gy GK (12)	T-RT
		(III)
11	54/M	AA	59.4 Gy IMRT (11)	T-RT
		(III)
12	38/M	Ana. GG	54 Gy IMRT (24)	T-RT
		(III)	12 Gy GK (11)
13	50/M	GBM (IV)	60 Gy IMRT (1)	T-RT
14	42/M	Ana. OA	59.4 Gy IMRT (29)	T-RT
		(DD-III)
15	25/M	AA	None	None
		(DD-III)
16	48/F	OA	59.4 Gy 3D-C (76)	T-RT
		(III)
17	53/M	Ana. ODG	None	None
		(DD-III)
18	62/F	GBM	60 Gy 3D-C (8)	T-RT
		(IV)	12 Gy GK (7)
19	25/M	GBM	60 Gy 3D-C (19)	T-RT & B
		(IV)
20	46/F	Ana. ODG	None	None
		(DD-III)
21	40/F	AA	None	None
		(III)
22	49/M	AA	None	None
		(DD-III)
23	73/F	GBM	34 Gy IMRT (1)	T-RT
		(IV)
24	34/M	AA	None	None
		(DD-III)

Note:—AA indicates anaplastic astrocytoma; Ana. GG, anaplastic ganglioglioma; Ana. ODG, anaplastic oligodendroglioma; Ana. OA, anaplastic oligoastrocytoma; DD = dedifferentiated from previous low-grade tumor; IMRT, intensity-modulated radiation therapy; GK, gamma knife; 3D-C, 3D conformal; T-RT, temodar (with initial radiation therapy); B, prior bevacizumab therapy; RT, radiation therapy.

^aAll patients underwent prior surgical treatment for their primary tumors.