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Performance of Frontier ASPECTS in the test set in comparison to reference standard with optimal thresholds defined in the training set
| ASPECTS region | Threshold value (%) | Specificity (%) | Sensitivity (%) | TP | TN | FP | FN | AUC | (95% CI) |
|---|---|---|---|---|---|---|---|---|---|
| CN, IC, INS, LN | 5.6 | 89 | 57 | 353 | 711 | 87 | 269 | 0.795 | (0.771–0.819) |
| M1–M6 | 4.7 | 89 | 41 | 154 | 1565 | 191 | 220 | 0.750 | (0.722–0.778) |
| Combined | 89 | 51 | 507 | 2276 | 278 | 489 | |||
| All 10 regions | 4.9 | 89 | 54 | 533 | 2274 | 280 | 463 | 0.713 | (0.692–0.733) |
