Table 3.
Agreement comparison of Frontier ASPECTS and observers and agreement between observers in the test set (n = 355)
| Agreement on normal regions (n) | Agreement on abnormal regions (n) | Overall agreement (%) | Trichotomizeda ASPECTS agreement (%) | ASPECTS ICC (95% CI) | |
|---|---|---|---|---|---|
| Frontier ASPECTS (default thresholds) vs. reference standard | 2046 | 613 | 2785 (78) | 200/355 (56) | .494 (.412–.569) |
| Frontier ASPECTS (optimized thresholds for [CN/ IC/ INS/ LN] & [M1-M6 regions]) vs. reference standard | 2276 | 507 | 2783 (78) | 213/355 (60) | .526 (.447–.597) |
| Frontier ASPECTS (1 optimized threshold for all 10 regions) vs. reference standard | 2274 | 533 | 2807 (79) | 210/355 (59) | .537 (.459–.607) |
| observer 1 vs. reference standard | 2430 | 536 | 2742 (84) | 212/355 (60) | .464 (.378–.542) |
| observer 2 vs. reference standard | 2353 | 389 | 2742 (77) | 204/355 (57) | .383 (.291–.468) |
| observer 1 vs. observer 2 | 2713 | 337 | 3050 (86) | 238/273 (77) | .667 (.605–.721) |
aclassification by ASPECTS 0–4, 5–7 and 8–10