Table 3:

Sensitivity and specificity for the presence of SWI-filtered phase, T2, and their overlapping white matter signal abnormalities among patients with clinically isolated syndrome, other neurologic disorders, and age- and sex-matched healthy controls^a

	CIS vs HC			CIS vs OND
	Sensitivity	Specificity	Accuracy	Sensitivity	Specificity	Accuracy
Phase WM-SA
Total	70.8	76.6	73.7b	70.8	76.7	73.1b
Periventricular	66.7	76.6	71.6b	66.7	80	71.8b
Juxtacortical	27.1	100	63.2b	27.1	90	51.3
Infratentorial	0	100	–	0	100	–
Deep WM	27.1	93.8	60c	27.1	86.7	50
T2 WM-SA
Total	93.9	68.8	81.4b	95.8	13.3	64.1
Periventricular	93.8	91.5	92.6b	93.8	13.3	62.8
Juxtacortical	52.1	93.6	72.6b	52.1	83.3	64.1c
Infratentorial	18.8	100	58.9c	18.8	96.7	48.7
Deep WM	81.3	74.5	77.9b	81.3	53.3	70.5
Overlapping
Total	55.1	100	77.3b	56.3	90	69.2b
Periventricular	54.2	100	76.8b	54.2	90	67.9b
Juxtacortical	8.3	100	53.7b	8.3	93.3	41
Infratentorial	0	100	–	0	100	–
Deep WM	18.8	100	59c	18.8	93.3	47.4

Note:— indicates not applicable.

^aSensitivity and specificity were computed using cross-tabulations.

^bP < .001.

^cP < .01. P values have been corrected for false discovery rate at the P < .05 level.