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. 2014 Oct;35(10):1916–1923. doi: 10.3174/ajnr.A3969

Table 4:

Sensitivity and specificity for the presence of multiple SWI-filtered phase signal abnormalities and fulfillment of the McDonald 200530 and 20107 criteria for dissemination in space between patients with clinically isolated syndrome and other neurologic disordersa

CIS vs. OND
Sensitivity Specificity Accuracy
≥2 Phase WM-SAs 56.3 83.3 66.7b
≥3 Phase WM-SAs 43.8 90 61.5c
≥4 Phase WM-SAs 43.8 93.3 62.8b
McDonald 2005 criteria for DIS 52.1 80 62.8c
McDonald 2010 criteria for DIS 62.5 76.7 67.9c
≥2 Phase + McDonald 2005 criteria for DIS 33.3 90 55.1
≥2 Phase + McDonald 2010 criteria for DIS 39.6 90 58.9c

Note:P < .05. P values have been corrected for false discovery rate at the P < .05 level.

a

Sensitivity and specificity were computed using cross-tabulations.

b

P < .001.

c

P < .01.