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. 2014 Sep;35(9):1700–1706. doi: 10.3174/ajnr.A3946

Cortical areas >40 mm2 with significant differences between patients with Kallmann syndrome and controls by sulcation, curvature, and cortical thickness analyses

Hemisphere Size (mm2) Local Maximum, Talairach
FDR Threshold Cerebral Region
X Y Z
Sulcation
    Right 394.05 11.2 13.8 −14.9 3.3429 Olfactory sulcus and contiguous cortex of the rectus gyrus
    Right 325.72 16.4 28.7 −23.7 3.3429 Medial orbital-frontal gyrus
    Left 518.07 −9.8 16.0 −15.4 3.3159 Olfactory sulcus and contiguous cortex of the rectus gyrus
    Left 252.41 −19.6 33.2 −17.3 3.3159 Medial orbital-frontal gyrus
Curvature
    Right 372.85 14.4 32.3 −25.3 3.4704 Medial orbital-frontal gyrus
    Right 77.61 11.7 16.6 −14.2 3.4704 Olfactory sulcus
    Right 44.71 11.5 37.9 −19.1 3.4704 Olfactory sulcus
    Left 196.94 −11.6 38.7 −20.0 3.4704 Olfactory sulcus
    Left 114.79 −19.6 32.7 −14.9 3.4704 Medial orbital-frontal gyrus
Thickness
    Right 568.97 −14.1 30.7 −19.2 3.3834 Olfactory sulcus and contiguous cortex of the rectus and medial orbital-frontal gyri
    Left 686.38 13.7 33.4 −23.3 3.2803 Olfactory sulcus and contiguous cortex of the rectus and medial orbital-frontal gyri
    Left 78.39 12.7 48.6 33.5 3.2803 Medial orbital-frontal sulcus
    Left 40.54 45.2 −62.3 36.9 3.2803 Lateral orbital-frontal gyrus

Note:—↑ indicates that patients with KS showed increased sulcation, curvature, and cortical thickness; ↓, patients with KS showed decreased sulcation, curvature, and cortical thickness; FDR, false discovery rate.