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. 2021 Mar 16;11:6028. doi: 10.1038/s41598-021-85382-4

Table 1.

Clinical features of bacterial meningitis at presentation.

Variables Total
(n = 161)
Community-acquired
(n = 43)
Healthcare-related
(n = 118)
P
Age, years 55.9 ± 15.5 64.6 ± 12.5 52.7 ± 15.3  < 0.001
Male 50.9% 60.5% 47.5% 0.144
Body temperature, °C 37.6 ± 1.0 37.6 ± 1.1 37.6 ± 1.0 0.948
Body temperature ≥ 38 °C 38.0% 37.2% 38.3% 0.904
Fever by history 88.2% 93.0% 86.4% 0.252
Neck stiffness* 62.5% 73.7% 52.4% 0.049
Mental status change 52.2% 74.4% 44.1% 0.001
GCS score 12.3 ± 3.8 11.2 ± 4.0 12.7 ± 3.7 0.032
GCS score ≤ 8 20.5% 30.2% 16.9% 0.065
Symptom triad* 31.3% 47.4% 16.7% 0.003
Systolic BP, mmHg 134.5 ± 26.1 142.4 ± 29.8 131.6 ± 24.1 0.037
Diastolic BP, mmHg 79.4 ± 16.0 81.3 ± 13.9 78.7 ± 16.7 0.373
Predisposing factors
Immunocompromised 19.3% 11.6% 22.0% 0.138
Concurrent infections 27.3% 14.0% 32.2% 0.027
Diabetes mellitus 17.4% 27.9% 13.6% 0.034
Recent neurosurgery† 47.2% 0 64.4%  < 0.001
Neurosurgical devices 46.0% 0 62.7%  < 0.001
CSF leakage 7.5% 2.3% 9.3% 0.184

Data are presented as mean ± SD or %. *Data were available in 85 cases. †Recent neurosurgery refers to neurosurgery within 1 month of the onset of meningitis. Abbreviations: GCS, Glasgow coma scale; CSF, cerebrospinal fluid.