Table 3.

Therapeutic Goals and Treatable Traits in Asthma

Therapeutic Goals	Treatable Traits	Biomarker Associated to Therapeutic Trait
Reduction of symptoms:	-Bronchial obstruction	-FEV1
-Dyspnoea	-Non-adherence	-Questionnaires
-Night awakenings	-Aggravating factors (allergens,	-Environmental levels
-Health-related quality of life	environmental pollution, etc.)
Reduction of risk:	-Allergy	-Specific IgE, skin prick tests
-Reduce mortality	-Smoking	-CO-oximetry
-Reduce progression of the disease	-Comorbidities	-Variable in each case
-Prevent exacerbations	-Eosinophilia	-Eosinophils in blood or airways
-Reduce adverse effects of medication	-Chronic infection	-Germ isolation