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. 2021 Mar 12;16:2107–2121. doi: 10.2147/IJN.S295565

Figure 2.

Figure 2

Cell viability of B16F10 cells treated with different concentrations of DTIC, DTIC@MSN and DTIC@CMSN for 24 h (A) or 48 h (B). (C) Apoptosis by flow cytometry assay in B16F10 cells induced by medium alone as negative control, DTIC, DTIC@MSN and DTIC@CMSN for 24 h. (D) Corresponding percentages of living, early apoptotic, late apoptotic, and necrotic tumor cells under different treatments. Error bars were calculated based on six samples. *P < 0.05.