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. 2014 Jan;35(1):106–112. doi: 10.3174/ajnr.A3653

Table 2:

Demographic and clinical characteristics of non-familial healthy control subjects and the healthy relatives of patients with multiple sclerosis

Non-Familial HCs (n = 82) Healthy Relatives of Patients with MS (n = 68) P Value
Age, y, mean (SD) median 39.8 (14.3) 43 39.5 (16.6) 43 .917
Sex, female n (%) 57 (69.5) 45 (66.2) .663
Race/ethnicity, n (%) .180
    White 64 (78.1) 62 (91.2)
    Black 12 (14.6) 4 (5.9)
    Other 6 (7.3) 2 (2.9)
Vascular risk factors, n (%)
    Heart disease 8 (9.8) 13 (19.1) .085
    Smoking 22 (27.5) 19 (27.9) .979
    Hypertension 17 (20.7) 15 (22.1) .442
    Obesity n (%)a .582
    BMI <18.5 2 (2.4) 2 (2.9)
    BMI 18.5–24.9 34 (41.5) 25 (36.8)
    BMI 25–29.9 26 (31.7) 17 (25.0)
    BMI >30 13 (15.8) 18 (26.5)
Autoimmune diseases, n (%)
    Systemic lupus erythematosus 0 0 NA
    Rheumatoid disorder 1 (1.2) 2 (2.9) .474
    Psoriasis 0 1 (1.5) .279
    Diabetes mellitus type 1 1 (1.2) 0 .352
Migraine, n (%) 10 (12.2) 13 (19.1) .282

Note:—BMI indicates body mass index.

BMI <18.5 represents underweight, BMI 18.5–24.9 represents normal weight, BMI 25–29.9 represents overweight, and BMI >30 represents obesity. The differences between the groups were compared by means of the Student t test or the χ2 test.

a

Data missing for 13 subjects.