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. 2021 Mar 3;11:559148. doi: 10.3389/fcimb.2021.559148

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Copyright © 2021 Zhang, Li, Cao and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The different gastric microbiota profile between cardia cancer and non-cardia cancer. (A) There was no significant difference in Chao1 index between gastric cardia cancer (GCC) and gastric non-cardia cancer (GNCC) groups. (B) Shannon index was higher in GNCC group compared with GCC group (Student’s t-test was used to compare the two groups). (C) Partial least squares Discriminant Analysis (PLS-DA) revealed different microbial community structures between the two groups (ANOSIM was used to evaluate the similarity between groups). (D) Relative abundance of phyla in the two groups. (E) Relative abundance of genera in the two groups.