Table 3:

Clinical and MRI findings of the patients with MS and the NCs after 3 years of follow-up

	NC (n = 28)	cMS (n = 35)	aMS (n = 57)
EDSS change	n.a.	0.8 ± 0.4 (0–3.5)	1.0 ± 0.5(0–3.0)
Global Δ-GMf %	0.2 ± 0.1 (0.1–0.5)	0.5 ± 0.2 (0.2–1.1)*	0.5 ± 0.2 (0.3–1.0)*
New T2-WM lesions	n.a	1.8 ± 1.0 (0.1–5.4)	1.9 ± 1.5 (0–8)
New CLs	n.a.	1.5 ± 1.3 (0–8)	1.1 ± 1.5 (0–7)

Note:—Data are reported as mean ± standard deviation (range).

Global Δ-GMf (%) indicates percentage of GM fraction change between T0 and T3; n.a., not applicable; T2-WM lesions, white matter lesions.

^*P < 0.001 (compared with NC).