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CTA definition of extracranial and intracranial large-vessel stenosis. Compared with the nonobstructive ICA disease (A), extracranial carotid artery stenosis was defined as evidence of >50% stenosis based on the NASCET criteria (B). Similarly, compared with the large intracranial vessel disease (<50%, M1, C), intracranial stenosis was defined as >50% stenosis in either the middle (M1) (D), anterior (A1), or posterior cerebral arteries (P1) on CTA, on either side.
