Table 3:

Multivariate predictors of lnWMHV in 201 patients with AIS

Predictors	Estimate	T Value	P Value
Model 1a		F = 13.42	<.0001
Age (yr)	0.03	6.34	<.0001d
Sex	0.07	0.45	.65
SBP	0.01	2.24	.03d
HTN	0.12	0.68	.50
Extracranial carotid stenosis	0.03	0.16	.87
Model 2b		F = 11.45	<.0001
Age (yr)	0.03	6.19	<.0001d
Sex	0.11	0.66	.51
SBP	0.01	2.43	.02d
HTN	0.14	0.79	.43
Extracranial carotid stenosis	0.11	0.60	.55
Intracranial arterial stenosis	−0.12	−0.69	.49
Model 3c		F = 2.35	.10
Intracranial arterial stenosis	−0.01	−0.05	.96
Extracranial carotid stenosis	0.42	2.06	.04d

^aModel includes all univariate predictors with P < 0.2.

^bModel includes all univariate predictors with P < 0.2 and intracranial arterial stenosis.

^cExploratory model of the effect of subtype of large-artery stenosis on white matter hyperintensity burden.

^dStatistically significant.