Table 6:
Summary of previous Pipeline series in comparison with this series
Series | No. of Patients/AA | No of AA W Previous TX Failurea (%) | No of AA Treated W Adjunctive Coilingb (%) | Morbidityc and Mortality | Complete Occlusion at 6-Month DSA (%) | Control Angiography (%) | Retx No of AA (%) | Peri-Post-Operative Intracranial Bleeding | Perforator Infarct | In-Stent Stenosis All %/Requiring TX % PAO |
---|---|---|---|---|---|---|---|---|---|---|
Lylyk et al 200920,d | 53/63 | 23/63 | 4/63 (6%) | 0 | 93% | 100% | 0 | 0 | 0 | 10%/0 |
(37%) | 0% | PAO: 0 | ||||||||
Szikora et al 201021,e | 18/19 | 1/19 | 10/19 (53%) | 5.6% | 94.4% | 94.7% | 0 | 1/18f | 0 | 0 |
(5.3%) | 5.6% | 5.6% | PAO:5.6% | |||||||
Nelson et al 201123 | 31/31 | 12/31 | 16/31 (52%) | 6.5% | 93.3% | 96.8% | 0 | 1/31g | 1/31 | 0 |
(38.7%) | 0% | 3.2% | (3.2%) | PAO:0 | ||||||
Fischer et al 201124 | 88/101 | 30/101) | 3/101 (3%) | 4% | 52% | 89% | 8/101 | 4/88h | 0 | 2.3%/0 |
(29.7%) | 2% | 7.9% | 4.6% | PAO:2.3% | ||||||
McAuliffe et al 201234 | 54/57 | 16/57 | 12/68 (18%) | 0 | 85.7% | 98.2% | 2/57i | 0 | 0 | 3.5%/0 |
(28.1%) | 0% | 3.5% | PAO:0 | |||||||
Saatci et al 2012 | 191/251 | 34/251 | 11/251 (4%) | 1% | 91.2 % | 95.2 % | 8/251 | 3/191j | 1/191 | 4.2%/1.6% |
(13.5%) | 0.5% | 3.2% | 1.6% | 0.5% | PAO:0 |
Note:—AA indicates aneurysms; TX, treatment; W, with DSA; Retx retreatment.
Refers to the aneurysms that underwent previous endovascular or surgical treatment, including the failed treatment, incomplete treatment, and recurrences.
Refers to the aneurysms in which coiling was performed as an adjunctive treatment in the same session with PED placement.
Temporary deficits not included.
Six (d) and 9 (e) aneurysms of these series were also included in the PITA trial.
Refers to the rupture of a coexisting aneurysm.
Refers to an iatrogenic ICA rupture.
Includes 1 aneurysm rupture and 3 parenchymal hemorrhages.
Additional treatment required due to PED displacement in 2 aneurysms.
Includes 1 aneurysm rupture and 2 parenchymal hemorrhages.