Patient demographics and clinical characteristics

	Patients Diagnosed with Osteoradionecrosis	Patients Diagnosed with Tumor Recurrence	P Value
No. of patients	46	17	NA
Average age (yr)	62	69	.11
Age range (yr)	33–93	53–85
% Men (No.)	76.1 (35)	77.5 (13)	1.00
Primary malignancy site	Oral Cavity (n = 27), oropharynx (n = 11), parotid (n = 5), NPC (n = 2) unknown (n = 1)	Oral cavity (n = 15), oropharynx (n = 1), sinonasal (n = 1)
Primary malignancy histology	Squamous cell (n = 44), adenoid cystic (n = 2)	Squamous cell (n = 17)
Mean interval (range) between last RT and detection of abnormality (mo)	40.56 (6–110)	48.82 (5–98)	.19

Note:—NA indicates not applicable; NPC, nasopharyngeal cancer; RT, radiation therapy.