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. 2021 Mar 3;11:619517. doi: 10.3389/fonc.2021.619517

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Copyright © 2021 Li, Wang, Yuan, Ma, Jiang, Li, Zhang and Xiu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Venn map illustrating the identification of the differentially expressed MRGs (A). Forest map of MRGs related to pancreatic adenocarcinoma (PAAD) survival by univariate Cox regression analysis (B). Least Absolute Shrinkage and Selection Operator (LASSO) coefficient spectrum of the nine MRGs selected by the univariate Cox regression. Generate a coefficient distribution map for a logarithmic (λ) sequence (C). Selecting the best parameters for PAAD in the LASSO model (λ) (D). Kaplan–Meier survival analysis of TCGA-PAAD patients stratified by the median value of risk score (E).