Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 3;12:638676. doi: 10.3389/fimmu.2021.638676

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Pan, Huang, Sekar, Huang, Lin and Hsieh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Suppression of MSU-induced mitochondrial production of the ROS by DcR3.Fc and HBD.Fc in M-Mϕ and GM-Mϕ. M-Mϕ (A) and GM-Mϕ (B) treated with hIgG, DcR3.Fc, or HBD.Fc- (3 μg/ml of each) were stained with MitoSOX (2.5 μM, 30 min) and then stimulated with MSU (300 μg/ml) for 1.5 or 3 h. The MitoSOX fluorescence was detected through the PE-channel by flow cytometry, and the median fluorescence intensity (MFIs) were shown in each histogram. The data shown were mean ± SD of three independent experiments. The statistical significance was determined by one-way ANOVA. *p < 0.05 was obtained by comparing DcR3.Fc- or HBD.Fc-treated group to hIgG-group.