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Less amounts of inflammatory cytokines and chemokines were induced in DcR3-tg mice by MSU. MSU (3 mg/mouse) or PBS was injected into the air pouch of DcR3-tg or WT B6 mice. Mice were sacrificed, and the lavage fluid was collected at indicated times. The data shown were mean ± SD of three independent experiments. The statistical significance was determined by the student t-test. *p < 0.05 and **p < 0.01 were obtained by comparing DcR3-tg mice to WT mice.
