TABLE 1.

Classification of peptide-based hydrogels assuming a cross-β structure with the relative reference.

HGs formed by peptides with alternating sequences
Alternation of apolar residues with both positively and negatively charged residues	Alternation of apolar residues with either positively or negatively charged residues
Ac-(AEAEAKAK)2-NH2 [1]	PE(LE)5P-OH[12]
Ac-RADARADARADARADA-NH2[2]	Ac-(IKIK)2-NH2[13]
Ac-RARADADARARADADA-NH2[2]	Ac-(FKFK)2-NH2[13]
Ac-(FKFE)n-NH2; n = 2,3,4[3]	Ac-(F5FKF5FK)2-NH2[13]
FEFEFKFK-OH [4]	Ac-(ChaKChaK)2-NH2[13]
(FEFEFKFK)2-OH[5]	Ac-(VK)5-NH2[13]
Ac-(VKVE)3-NH2[6]	(VK)4V-NH2[13]
VKVKVEVK-OH[7]	(VK)5V-NH2[13]
VEVKVEVK-OH[7]	(VK)6V-NH2[13]
VEVEVEVK-OH[7]	(VR)6V-NH2[14]
Ac-(IKIE)3-NH2[8]	(IK)6I-NH2[14]
Ac-RLDLRLALRLDLR-NH2[9]	(LK)6L-NH2[14]
FFKLVFF-PEG2k[10]	Ac-(AAAK)3-NH2[15–17]
FFKLVFF-PEG3k[10]	Ac-(AAAK)4-NH2[15–17]
VEQLTEEQKNEFKAAFDIFVLGA-OH[11]	VKVKVKVKVDPPTKVKVKVKV-NH2[18]
Alternation of apolar and uncharged polar residues	Gln-rich peptides
PEG8-(FY)3-NH2 [19]	Ac-QQRQQQQQEQQ-NH2[23]
H-(Nal-DOPA)3-NH2[20]	Ac-QQRFQWQFEQQ-NH2[23]
Ac-K2(SL)6K2-NH2[21]	Ac-QQKFQFQFEQQ-NH2[24]
Ac-K2(QL)6K2-NH2[21]
Ac-K2(TL)6K2-NH2[21]
GSFSIQYTYHV-OH[22]
HGs formed by blocks of polar/apolar stretchs	HGs formed by conjugating single amino acids or dipeptides
Ac-LIVAGD-OH[25]	Fmoc-F[30]
Ac-LIVAGDD-OH[25]	Fmoc-Y[31]
Ac-IVAGD-OH[25]	Fmoc-FF-OH[32,33]
Ac-IVD-OH[25]	Fmoc-FG-OH[34]
Ac-ILVAGD-OH[25]	Fmoc-DOPA-DOPA[35]
Ac-ILVAGS-OH[25]	Fmoc-F-Nphe[36]
Pal-VVVVAA-EEE-OH[26]	Fmoc-Nphe-F[36]
Pal-VVAAAA-EEE-OH[26]	Fmoc-Nphe-Nphe[36]
Pal-AAAVVV-EEE-OH[26]	Nvoc-FF[37]
Pal-VVVVAAAA-EEE-OH[26]
Pal-VVVAAA-EEE-OH[26]
Pal-VVAA-EEE-OH[26]
Pal-VVVVAA-EEE-OH[26]
Pal-VVAAAA-EEE-OH[26]
Pal-AAAVVV-EEE-OH[26]
Pal-GGGGGGG-ERGDS-OH[27]
Pal-GGGGGGNMeG-ERGDS-OH[27]
Pal-GGGGGNMeGG-ERGDS-OH[27]
Pal-GGGGNMeGGG-ERGDS-OH[27]
Pal-GGGGGNMeGNMeG-ERGDS-OH[27]
Pal-V3K2-NH2[28]
Lar-V3K2-NH2[28]
Myr-V3K2-NH2[28]
Myr-AA-OH[28]
GSSAAAAAAAASGPGGYGPENQG PSGPGGYGPGGP[29]

[1] Zhang et al. (1993a,b), [2] Yokoi et al. (2005), [3] Swanekamp et al. (2014), [4] Saiani et al. (2009), [5]Wang et al. (2005), [6] Bowerman et al. (2011), [7] Roberts et al. (2012), [8] Caplan et al. (2002): [9] Nagai et al. (2012), [10] Castelletto et al. (2010), [11] De Leon-Rodriguez L. M. et al. (2016), [12] Rapaport et al. (2008), [13] Bowerman et al. (2011), [14] Geisler and Schneider (2012), [15] Measey and Schweitzer-Stenner (2006), [16] Measey et al. (2010), [17] Jang et al. (2009), [18] Nagy-Smith et al. (2015), [19] Diaferia et al. (2018b), [20] Diaferia et al. (2020), [21] Galler et al. (2010), [22] Frohm et al. (2015), [23] Davies et al. (2006): [24] Dawson et al. (1994), [25] Mishra et al. (2011), [26] Pashuck (2010): [27] Paramonov et al. (2006), [28] Wang et al. (2015), [29] Schacht and Scheibel (2011), [30] Singh et al. (2015), [31] Yang et al. (2021), [32] Mahler et al. (2006), [33] Jayawarna et al. (2006), [34] Tang et al. (2011), [35] Fichman et al. (2014a), [36]Rajbhandary and Nilsson (2017), [37] Roth-Konforti et al. (2018).