Table 5.
Multiple regression model—dependent variable NFL, NFD, NBD and TC*.
SNP parameter | Variables | B non standardized | SD | B standardized | P value* | Tolerance | VIF |
---|---|---|---|---|---|---|---|
NFL (µm/mm2) | Constant | 28,349.19 | 11,070.01 | 0.013 | |||
Age (years) | − 61.446 | 14.505 | − 0.447 | < 0.001 | 0.753 | 1.328 | |
K (D) | − 176.681 | 138.564 | − 0.138 | 0.207 | 0.718 | 1.392 | |
CD (mm) | − 1030.58 | 539.281 | − 0.215 | 0.060 | 0.660 | 1.516 | |
CCT (mm) | 2.466 | 5.415 | 0.044 | 0.650 | 0.885 | 1.129 | |
Sph (D) | − 158.433 | 63.866 | − 0.249 | 0.016 | 0.832 | 1.201 | |
Cyl (D) | − 656.134 | 212.06 | − 0.297 | 0.003 | 0.908 | 1.101 | |
NFD (no./mm2) | Constant | 145.537 | 140.073 | 0.042 | |||
Age (years) | − 0.467 | 0.184 | − 0.298 | 0.013 | 0.753 | 1.328 | |
K (D) | − 1.407 | 1.753 | − 0.096 | 0.425 | 0.718 | 1.392 | |
CD (mm) | 3.959 | 6.824 | 0.073 | 0.564 | 0.660 | 1.516 | |
CCT (mm) | − 0.101 | 0.069 | − 0.159 | 0.146 | 0.885 | 1.129 | |
Sph (D) | − 2.119 | 0.808 | − 0.292 | 0.011 | 0.832 | 1.201 | |
Cyl (D) | − 1.464 | 2.683 | − 0.058 | 0.587 | 0.908 | 1.101 | |
NBD (no./mm) | Constant | − 117.051 | 69.774 | 0.048 | |||
Age (years) | 0.012 | 0.091 | 0.009 | 0.845 | 0.753 | 1.328 | |
K (D) | 2.423 | 0.873 | 0.354 | 0.007 | 0.718 | 1.392 | |
CD (mm) | 3.548 | 3.399 | 0.139 | 0.300 | 0.660 | 1.516 | |
CCT(mm) | 0.01 | 0.034 | 0.001 | 0.902 | 0.885 | 1.129 | |
Sph (D) | − 0.407 | 0.403 | − 0.12 | 0.315 | 0.832 | 1.201 | |
Cyl (D) | − 3.911 | 1.337 | − 0.332 | 0.005 | 0.908 | 1.101 | |
TC | (Constant) | 57.13 | 48.439 | 0.242 | |||
Age | − 0.237 | 0.063 | − 0.427 | < 0.001 | 0.753 | 1.328 | |
K (D) | − 0.375 | 0.606 | − 0.073 | 0.538 | 0.718 | 1.392 | |
CD (mm) | − 0.393 | 2.36 | − 0.02 | 0.868 | 0.660 | 1.516 | |
CCT(mm) | − 0.016 | 0.024 | − 0.072 | 0.498 | 0.885 | 1.129 | |
Sph (D) | − 0.612 | 0.279 | − 0.239 | 0.032 | 0.832 | 1.201 | |
Cyl (D) | − 0.673 | 0.928 | − 0.076 | 0.471 | 0.908 | 1.101 |
*NFL nerve fiber length (µm/mm2), NFD nerve fiber density (no./mm2), NBD nerve beadings density (no./mm), TC tortuosity coefficient, K corneal curvature (D diopter), CD corneal diameter (mm), CCT corneal thickness (µm), Sph sphere (D diopter), Cyl cylinder (D diopter).
**Bold values denote statistical significance at the p-value < 0.05.