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. 2021 Mar 16;11:5962. doi: 10.1038/s41598-021-85270-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Measurement of repair tissue reflectivity following retinal pigment epithelial (RPE) tear by means of spectral-domain optical coherence tomography (SD-OCT). (A) and (B) show blue-light autofluorescence and SD-OCT scans of a patient at baseline and at 12 months of follow-up, respectively. Red dashed box highlights the formation of the RPE-subretinal hyperreflective tissue complex that was quantitatively measured after manual delineation. RPE-Bruch’s membrane complex, used as internal reference, is presented in the green dashed box.