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. 2021 Mar 16;9:18. doi: 10.1038/s41413-021-00139-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — 3D printing of Fe-CaSiO₃ composite scaffolds for tumor therapy and bone regeneration. a The fabrication of Fe-CaSiO₃ composite scaffolds for short-term tumor therapy and long-term bone regeneration. b Infrared (IR) radiation thermal images of tumor-bearing mice after irradiation with an 808 nm laser for 600 s. The photographs of the tumors from the six groups are from day 15. c Micro-CT images (a–c) and histological analysis (d–f) of the bone defects in the CaSiO₃, Fe, and Fe-CaSiO₃ (30CS) groups postsurgery in a rabbit critical-sized femoral defect model. The statistical analysis of the defects (g, h) and histomorphometric measurements of in vivo osteogenesis (i) in the CaSiO₃, Fe, and 30CS groups 8 weeks post surgery. Reprinted with permission from ref. ⁹⁹ © 2018, Nature Publishing Group