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. 2021 Mar 3;15:642589. doi: 10.3389/fnins.2021.642589

TABLE 2.

Correlations of the sciatic nerve’s FA with clinical, epidemiological, and serological data of diabetes patients, prediabetes patients, and controls.

FA diabetes patients
FA prediabetes patients
FA controls
r p r p r p
Age (years) –0.48 < 0.001 0.44 0.202 –0.63 0.001
Body mass index (kg/m2) –0.18 0.140 –0.08 0.832 0.03 0.881
NDS –0.53 < 0.001 –0.58 0.082 –0.47 0.017
NSS –0.20 0.106 –0.57 0.107 –0.36 0.107
HbA1c (%) 0.15 0.211 –0.07 0.844 –0.42 0.039
Cystatin C (mg/l) –0.45 < 0.001 –0.27 0.489 –0.22 0.320
Glomerular filtration rate (ml/min) 0.46 < 0.001 0.21 0.571 0.23 0.291
Triglycerides (mg/dl) 0.05 0.694 0.06 0.876 –0.04 0.867
Total serum cholesterol (mg/dl) 0.17 0.151 –0.10 0.776 –0.15 0.462
HDL cholesterol (mg/dl) 0.17 0.157 –0.11 0.762 0.07 0.728
LDL cholesterol (mg/dl) 0.10 0.414 0.05 0.770 –0.18 0.396
Sural NCV(m/s) 0.24 0.128 –0.28 0.505 –0.12 0.568
Sural SNAP (μV) 0.47 0.006 0.30 0.471 0.58 0.003
Tibial NCV (m/s) 0.47 < 0.001 0.61 0.081 0.35 0.099
Tibial CMAP (μV) 0.62 < 0.001 0.61 0.081 0.30 0.150
Peroneal NCV (m/s) 0.52 < 0.001 0.43 0.246 0.31 0.142
Peroneal CMAP (μV) 0.62 < 0.001 0.51 0.160 0.18 0.411
Total Pegboard Test score 0.52 < 0.001 0.79 0.007 0.76 < 0.001
Pegboard Test of dominant hand 0.61 < 0.001 0.65 0.044 0.64 0.001
Pegboard Test of non-dominant hand 0.43 < 0.001 0.71 0.022 0.55 0.005
Pegboard Test of both hands 0.38 0.002 0.70 0.024 0.59 0.002
Pegboard Assembly Test 0.46 < 0.001 0.71 0.022 0.61 0.001

NDS, Neuropathy Disability Score; NSS, Neuropathy Severity Score; HbA1c, glycated hemoglobin; GFR, glomerular filtration rate; HDL, high density lipoprotein; LDL, low density lipoprotein; NCV, nerve conduction velocity; m/s, meters per second; SNAP, sensory nerve action potential; CMAP, compound motor action potential; μV, microvolt.