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. 2020 Oct 9;3(1):fcaa130. doi: 10.1093/braincomms/fcaa130

Figure 6.

Figure 6

Seizure susceptibility. (A) Time to SE onset after i.p. pilocarpine injection onset in 15 WT and 13 SESN3-KO rats. (B) Time to SE onset after intra-hippocampal injection of KA in 9 WT rats and 9 SESN3-KO rats. (C) after discharge threshold (ADT) associated with minimal behavioural symptoms (i.e. 1–2 on Racine scale score, n = 11 rats per genotype) (D) Kindling development. Days to reach Class 2 or Class 5 seizures according to the Racine’s scoring scale, in 11 animals per genotype. In all panels, open circles represent WT and solid circles represent SESN3-KO rats. Statistical analysis: unpaired t-test with Welch’s correction. *P < 0.05; **P < 0.01.